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Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice

The global incidence of tuberculosis remains unacceptably high, with new preventative strategies needed to reduce the burden of disease. We describe here a method for the generation of synthetic self-adjuvanted protein vaccines and demonstrate application in vaccination against Mycobacterium tubercu...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hanna, Cameron C., Ashhurst, Anneliese S., Quan, Diana, Maxwell, Joshua W. C., Britton, Warwick J., Payne, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848748/
https://ncbi.nlm.nih.gov/pubmed/33468674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013730118
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