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Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice

The global incidence of tuberculosis remains unacceptably high, with new preventative strategies needed to reduce the burden of disease. We describe here a method for the generation of synthetic self-adjuvanted protein vaccines and demonstrate application in vaccination against Mycobacterium tubercu...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hanna, Cameron C., Ashhurst, Anneliese S., Quan, Diana, Maxwell, Joshua W. C., Britton, Warwick J., Payne, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848748/
https://ncbi.nlm.nih.gov/pubmed/33468674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013730118
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