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Synthetic protein conjugate vaccines provide protection against Mycobacterium tuberculosis in mice

The global incidence of tuberculosis remains unacceptably high, with new preventative strategies needed to reduce the burden of disease. We describe here a method for the generation of synthetic self-adjuvanted protein vaccines and demonstrate application in vaccination against Mycobacterium tubercu...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hanna, Cameron C., Ashhurst, Anneliese S., Quan, Diana, Maxwell, Joshua W. C., Britton, Warwick J., Payne, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848748/
https://ncbi.nlm.nih.gov/pubmed/33468674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013730118
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