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Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue
Amyloid-β (Aβ) fibrils exhibit self-propagating, molecular-level polymorphisms that may contribute to variations in clinical and pathological characteristics of Alzheimer’s disease (AD). We report the molecular structure of a specific fibril polymorph, formed by 40-residue Aβ peptides (Aβ40), that i...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7848700/ https://ncbi.nlm.nih.gov/pubmed/33431654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023089118 |
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