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Experimental constraints on quaternary structure in Alzheimer's β-amyloid fibrils

We describe solid state nuclear magnetic resonance (NMR) measurements on fibrils formed by the 40-residue β-amyloid peptide associated with Alzheimer's disease (Aβ(1-40)) that place constraints on the identity and symmetry of contacts between in-register, parallel β-sheets in the fibrils. We re...

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Autores principales: Petkova, Aneta T., Yau, Wai-Ming, Tycko, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435828/
https://ncbi.nlm.nih.gov/pubmed/16401079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051952q
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