Chargement en cours...

A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR

We present a structural model for amyloid fibrils formed by the 40-residue β-amyloid peptide associated with Alzheimer's disease (Aβ(1–40)), based on a set of experimental constraints from solid state NMR spectroscopy. The model additionally incorporates the cross-β structural motif established...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Petkova, Aneta T., Ishii, Yoshitaka, Balbach, John J., Antzutkin, Oleg N., Leapman, Richard D., Delaglio, Frank, Tycko, Robert
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC139214/
https://ncbi.nlm.nih.gov/pubmed/12481027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262663499
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!