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Coexisting Order and Disorder Within a Common 40-Residue Amyloid-β Fibril Structure in Alzheimer's Disease Brain Tissue
Fibrils formed by 40- and 42-residue amyloid-β (Aβ40 and Aβ42) peptides exhibit molecular-level structural polymorphisms. A recent screen of fibrils derived from brain tissue of Alzheimer's disease patients revealed a single predominant Aβ40 polymorph. We present solid state nuclear magnetic re...
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| 發表在: | Chem Commun (Camb) |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953852/ https://ncbi.nlm.nih.gov/pubmed/29707712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc01967c |
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