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Head-to-head study of oxelumab and adalimumab in a mouse model of ulcerative colitis based on NOD/Scid IL2Rγ(null) mice reconstituted with human peripheral blood mononuclear cells
This study's aim was to demonstrate that the combination of patient immune profiling and testing in a humanized mouse model of ulcerative colitis (UC) might lead to patient stratification for treatment with oxelumab. First, immunological profiles of UC patients and non-UC donors were analyzed f...
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| Udgivet i: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7847261/ https://ncbi.nlm.nih.gov/pubmed/33293281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.046995 |
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