A mouse model for ulcerative colitis based on NOD-scid IL2R γ(null) mice reconstituted with peripheral blood mononuclear cells from affected individuals

Animal models reflective of ulcerative colitis (UC) remain a major challenge, and yet are crucial to understand mechanisms underlying the onset of disease and inflammatory characteristics of relapses and remission. Mouse models in which colitis-like symptoms are induced through challenge with toxins...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Palamides, Pia, Jodeleit, Henrika, Föhlinger, Michael, Beigel, Florian, Herbach, Nadja, Mueller, Thomas, Wolf, Eckhard, Siebeck, Matthias, Gropp, Roswitha
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047691/
https://ncbi.nlm.nih.gov/pubmed/27491073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.025452
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