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Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rγ(null) mice engrafted with human peripheral blood mononuclear cells

Animal models mimicking human diseases have been used extensively to study the pathogenesis of autoimmune diseases and the efficacy of potential therapeutics. They are, however, limited with regard to their similarity to the human disease and cannot be used if the antagonist and its cognate receptor...

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Autors principals: Nolte, Thomas, Zadeh-Khorasani, Maryam, Safarov, Orkhan, Rueff, Franziska, Varga, Rita, Herbach, Nadja, Wanke, Rüdiger, Wollenberg, Andreas, Mueller, Thomas, Gropp, Roswitha, Wolf, Eckhard, Siebeck, Matthias
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Limited 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529345/
https://ncbi.nlm.nih.gov/pubmed/22822046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009167
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