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FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability
Common fragile sites (CFSs) are genomic regions frequently involved in cancer-associated rearrangements. Most CFSs lie within large genes, and their instability involves transcription- and replication-dependent mechanisms. Here, we uncover a role for the mitochondrial stress response pathway in the...
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| Publicado en: | Commun Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7846573/ https://ncbi.nlm.nih.gov/pubmed/33514811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01647-8 |
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