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Dicer prevents genome instability in response to replication stress

Dicer, an endoribonuclease best-known for its role in microRNA biogenesis and RNA interference pathway, has been shown to play a role in the DNA damage response and repair of double-stranded DNA breaks (DSBs) in mammalian cells. However, it remains unknown whether Dicer is also important to preserve...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Fragkos, Michalis, Barra, Viviana, Egger, Tom, Bordignon, Benoit, Lemacon, Delphine, Naim, Valeria, Coquelle, Arnaud
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633883/
https://ncbi.nlm.nih.gov/pubmed/31320994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27034
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