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Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

DNA synthesis in vitro has enabled the rapid production of reference standards. These are used as controls, and allow measurement and improvement of the accuracy and quality of diagnostic tests. Current reference standards typically represent target genetic material, and act only as positive control...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Madala, Bindu Swapna, Reis, Andre L. M., Deveson, Ira W., Rawlinson, William, Mercer, Tim R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846570/
https://ncbi.nlm.nih.gov/pubmed/33514761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81760-0
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