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Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

DNA synthesis in vitro has enabled the rapid production of reference standards. These are used as controls, and allow measurement and improvement of the accuracy and quality of diagnostic tests. Current reference standards typically represent target genetic material, and act only as positive control...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Madala, Bindu Swapna, Reis, Andre L. M., Deveson, Ira W., Rawlinson, William, Mercer, Tim R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846570/
https://ncbi.nlm.nih.gov/pubmed/33514761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81760-0
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