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Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

DNA synthesis in vitro has enabled the rapid production of reference standards. These are used as controls, and allow measurement and improvement of the accuracy and quality of diagnostic tests. Current reference standards typically represent target genetic material, and act only as positive control...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Madala, Bindu Swapna, Reis, Andre L. M., Deveson, Ira W., Rawlinson, William, Mercer, Tim R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846570/
https://ncbi.nlm.nih.gov/pubmed/33514761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81760-0
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