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Mechanism of C-type inactivation in the hERG potassium channel
The fast C-type inactivation displayed by the voltage-activated potassium channel hERG plays a critical role in the repolarization of cardiac cells, and malfunction caused by nonspecific binding of drugs or naturally occurring missense mutations affecting inactivation can lead to pathologies. Becaus...
Shranjeno v:
| izdano v: | Sci Adv |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Association for the Advancement of Science
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7846155/ https://ncbi.nlm.nih.gov/pubmed/33514547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd6203 |
| Oznake: |
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