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Functional Consequences of Methionine Oxidation of hERG Potassium Channels

Reactive species oxidatively modify numerous proteins including ion channels. Oxidative sensitivity of ion channels is often conferred by amino acids containing sulfur atoms, such as cysteine and methionine. Functional consequences of oxidative modification of methionine in hERG1 (human ether à go-g...

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Bibliographic Details
Main Authors: Su, Zhi, Limberis, James, Martin, Ruth L., Xu, Rong, Kolbe, Katrin, Heinemann, Stefan H., Hoshi, Toshinori, Cox, Bryan F., Gintant, Gary A.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905454/
https://ncbi.nlm.nih.gov/pubmed/17624316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.06.002
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