Llwytho...

Stereoselective Inhibition of the hERG1 Potassium Channel

A growing number of drugs have been shown to prolong cardiac repolarization, predisposing individuals to life-threatening ventricular arrhythmias known as Torsades de Pointes. Most of these drugs are known to interfere with the human ether à-gogo related gene 1 (hERG1) channel, whose current is one...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grilo, Liliana Sintra, Carrupt, Pierre-Alain, Abriel, Hugues
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Research Foundation 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153011/
https://ncbi.nlm.nih.gov/pubmed/21833176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2010.00137
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!