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Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses

Accumulation of misfolded host proteins is central to neuropathogenesis of numerous human brain diseases including prion and prion-like diseases. Neurons of retina are also affected by these diseases. Previously, our group and others found that prion-induced retinal damage to photoreceptor cells in...

詳細記述

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書誌詳細
出版年:Acta Neuropathol Commun
主要な著者: Striebel, James F., Race, Brent, Leung, Jacqueline M., Schwartz, Cindi, Chesebro, Bruce
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845122/
https://ncbi.nlm.nih.gov/pubmed/33509294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01120-x
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