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Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses
Accumulation of misfolded host proteins is central to neuropathogenesis of numerous human brain diseases including prion and prion-like diseases. Neurons of retina are also affected by these diseases. Previously, our group and others found that prion-induced retinal damage to photoreceptor cells in...
में बचाया:
में प्रकाशित: | Acta Neuropathol Commun |
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मुख्य लेखकों: | , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
BioMed Central
2021
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845122/ https://ncbi.nlm.nih.gov/pubmed/33509294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01120-x |
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