Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL

As the GroES/GroEL chaperonin system is the only bacterial chaperone that is essential under all conditions, we have been interested in the development of GroES/GroEL inhibitors as potential antibiotics. Using Escherichia coli GroES/GroEL as a surrogate, we have discovered several classes of GroES/G...

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Publicat a:mBio
Autors principals: Sivinski, Jared, Ambrose, Andrew J., Panfilenko, Iliya, Zerio, Christopher J., Machulis, Jason M., Mollasalehi, Niloufar, Kaneko, Lynn K., Stevens, Mckayla, Ray, Anne-Marie, Park, Yangshin, Wu, Chunxiang, Hoang, Quyen Q., Johnson, Steven M., Chapman, Eli
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844535/
https://ncbi.nlm.nih.gov/pubmed/33436430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02167-20
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