Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Non-small cell lung cancer (NSCLC) brain metastasis cell lines and in vivo models are not widely accessible. Herein we report on a direct-from patient-derived xenograft (PDX) model system of NSCLC brain metastases with genomic annotation useful for translational and mechanistic studies. Both heterot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baschnagel, Andrew M., Kaushik, Saakshi, Durmaz, Arda, Goldstein, Steve, Ong, Irene M., Abel, Lindsey, Clark, Paul A., Gurel, Zafer, Leal, Ticiana, Buehler, Darya, Iyer, Gopal, Scott, Jacob G., Kimple, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843608/
https://ncbi.nlm.nih.gov/pubmed/33510214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81832-1
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