Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils

Although very different in etiology and symptoms, numerous neurodegenerative diseases can be classified as proteinopathies. More so, evidence indicates that the key misfolded proteins at the basis of different neuropathies might share common mechanisms of propagation. As such, the prion-like spreadi...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Veys, Lien, Van houcke, Jessie, Aerts, Jeroen, Van Pottelberge, Sophie, Mahieu, Michel, Coens, Audrey, Melki, Ronald, Moechars, Dieder, De Muynck, Louis, De Groef, Lies
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843377/
https://ncbi.nlm.nih.gov/pubmed/33519421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.614587
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