Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils

Although very different in etiology and symptoms, numerous neurodegenerative diseases can be classified as proteinopathies. More so, evidence indicates that the key misfolded proteins at the basis of different neuropathies might share common mechanisms of propagation. As such, the prion-like spreadi...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Veys, Lien, Van houcke, Jessie, Aerts, Jeroen, Van Pottelberge, Sophie, Mahieu, Michel, Coens, Audrey, Melki, Ronald, Moechars, Dieder, De Muynck, Louis, De Groef, Lies
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843377/
https://ncbi.nlm.nih.gov/pubmed/33519421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.614587
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