Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils

Although very different in etiology and symptoms, numerous neurodegenerative diseases can be classified as proteinopathies. More so, evidence indicates that the key misfolded proteins at the basis of different neuropathies might share common mechanisms of propagation. As such, the prion-like spreadi...

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Detalles Bibliográficos
Publicado en:Front Aging Neurosci
Main Authors: Veys, Lien, Van houcke, Jessie, Aerts, Jeroen, Van Pottelberge, Sophie, Mahieu, Michel, Coens, Audrey, Melki, Ronald, Moechars, Dieder, De Muynck, Louis, De Groef, Lies
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843377/
https://ncbi.nlm.nih.gov/pubmed/33519421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.614587
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