Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils

Although very different in etiology and symptoms, numerous neurodegenerative diseases can be classified as proteinopathies. More so, evidence indicates that the key misfolded proteins at the basis of different neuropathies might share common mechanisms of propagation. As such, the prion-like spreadi...

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Dettagli Bibliografici
Pubblicato in:Front Aging Neurosci
Autori principali: Veys, Lien, Van houcke, Jessie, Aerts, Jeroen, Van Pottelberge, Sophie, Mahieu, Michel, Coens, Audrey, Melki, Ronald, Moechars, Dieder, De Muynck, Louis, De Groef, Lies
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843377/
https://ncbi.nlm.nih.gov/pubmed/33519421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.614587
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