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Fluidigm Based Single-cell Gene Expression Library Preparation from Patient-derived Small Intestinal Organoids

In this protocol, we describe our methods to isolate crypts from patients' biopsy samples and to culture human intestinal stem cells as it’s called “organoid.” Beyond that, we describe how to dissociate organoids cells into single cells for single-cell analysis as a further application. This pr...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Suzuki, Kohei, Okamoto, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842824/
https://ncbi.nlm.nih.gov/pubmed/33659432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3775
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