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Single cell transcriptomics of human organoid-derived enteroendocrine cell populations from the small intestine

Gut hormones control intestinal function, metabolism and appetite, and have been harnessed therapeutically to treat type 2 diabetes and obesity. Our understanding of the enteroendocrine axis arises largely from animal studies, but intestinal organoid models make it possible to identify, genetically...

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Bibliografische gegevens
Gepubliceerd in:J Physiol
Hoofdauteurs: Smith, Christopher A, Lu, Van B, Bakar, Rula Bany, Miedzybrodzka, Emily, Davison, Adam, Goldspink, Deborah, Reimann, Frank, Gribble, Fiona M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2024
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7617304/
https://ncbi.nlm.nih.gov/pubmed/39639676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP287463
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