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Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells

It has long been speculated that metabolites, produced by gut microbiota, influence host metabolism in health and diseases. Here, we reveal that indole, a metabolite produced from the dissimilation of tryptophan, is able to modulate the secretion of glucagon-like peptide-1 (GLP-1) from immortalized...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Chimerel, Catalin, Emery, Edward, Summers, David K., Keyser, Ulrich, Gribble, Fiona M., Reimann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308618/
https://ncbi.nlm.nih.gov/pubmed/25456122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.032
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