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High-throughput Flow Cytometry Assay to Investigate TDP43 Splicing Function

Mutations in RNA-binding proteins (RBPs) such as TDP43 are associated with transcriptome-wide splicing defects and cause severe neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The impact of RBP mutations on splicing function is routinely s...

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Bibliografiska uppgifter
I publikationen:Bio Protoc
Huvudupphovsmän: Schmidt, H. Broder, Rohatgi, Rajat
Materialtyp: Artigo
Språk:Inglês
Publicerad: Bio-Protocol 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842676/
https://ncbi.nlm.nih.gov/pubmed/33659560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3594
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