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High-throughput Flow Cytometry Assay to Investigate TDP43 Splicing Function
Mutations in RNA-binding proteins (RBPs) such as TDP43 are associated with transcriptome-wide splicing defects and cause severe neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The impact of RBP mutations on splicing function is routinely s...
में बचाया:
| में प्रकाशित: | Bio Protoc |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Bio-Protocol
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7842676/ https://ncbi.nlm.nih.gov/pubmed/33659560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3594 |
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