Expression of the of the androgen receptor governs radiation resistance in a subset of glioblastomas vulnerable to anti-androgen therapy

New approaches are needed to overcome intrinsic therapy resistance in glioblastoma (GBM). Because GBMs exhibit sexual dimorphism and are reported to express steroid hormone receptors, we reasoned that signaling through the androgen receptor (AR) could mediate therapy resistance in GBM, much as it do...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Werner, Christian K., Nna, Uchechi J., Sun, Hanshi, Wilder-Romans, Kari, Dresser, Joseph, Kothari, Ayesha U., Zhou, Weihua, Yao, Yangyang, Rao, Arvind, Stallard, Stefanie, Koschmann, Carl, Bor, Tarik, Debinski, Waldemar, Hegedus, Alexander M., Morgan, Meredith A., Venneti, Sriram, Baskin-Bey, Edwina, Spratt, Daniel E., Colman, Howard, Sarkaria, Jann N., Chinnaiyan, Arul M., Eisner, Joel R., Speers, Corey, Lawrence, Theodore S., Strowd, Roy E., Wahl, Daniel R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842184/
https://ncbi.nlm.nih.gov/pubmed/32796101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0095
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge