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Harnessing a Different Dependency: How to Identify and Target Androgen Receptor-Positive Versus Quadruple-Negative Breast Cancer

The androgen receptor (AR) is a promising therapeutic target for a subset of triple-negative breast cancers (TNBCs) in which AR is expressed. However, the mechanistic action of AR and the degree to which primary and metastatic tumors depend on AR, both before and after conventional treatment, remain...

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Detalhes bibliográficos
Publicado no:Horm Cancer
Main Authors: Christenson, Jessica L., Trepel, Jane B., Ali, Haythem Y., Lee, Sunmin, Eisner, Joel R., Baskin-Bey, Edwina S., Elias, Anthony D., Richer, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864529/
https://ncbi.nlm.nih.gov/pubmed/29340907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-017-0314-5
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