Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53–ROS–Mitochondrial Pathway

NFBD1, a signal amplifier of the p53 pathway, is vital for protecting cells from p53-mediated apoptosis and the early phase of DNA damage response under normal culture conditions. Here we investigated its expression in patients with nasopharyngeal carcinoma (NPC), and we describe the biological func...

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Detalhes bibliográficos
Publicado no:Oncol Res
Main Authors: Wang, Zhihai, Liao, Kui, Zuo, Wenqi, Liu, Xueliang, Qiu, Zhili, Gong, Zhitao, Liu, Chuan, Zeng, Quan, Qian, Yi, Jiang, Liang, Bu, Youquan, Hong, Suling, Hu, Guohua
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840771/
https://ncbi.nlm.nih.gov/pubmed/28081741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504016X14732772150226
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