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NFBD1/MDC1 Regulates Cav1 and Cav2 Independently of DNA Damage and p53

NFBD1/MDC1 is involved in DNA damage checkpoint signaling and DNA repair. NFBD1 binds to the chromatin component γH2AX at sites of DNA damage, causing amplification of ataxia telangiectasia-mutated gene (ATM) pathway signaling and recruitment of DNA repair factors. Residues 508–995 of NFBD1 possess...

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Hlavní autoři: Wilson, Kathleen A., Colavito, Sierra A., Schulz, Vincent, Wakefield, Patricia Heffernan, Sessa, William, Tuck, David, Stern, David F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901581/
https://ncbi.nlm.nih.gov/pubmed/21551225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0317
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