Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53–ROS–Mitochondrial Pathway

NFBD1, a signal amplifier of the p53 pathway, is vital for protecting cells from p53-mediated apoptosis and the early phase of DNA damage response under normal culture conditions. Here we investigated its expression in patients with nasopharyngeal carcinoma (NPC), and we describe the biological func...

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Vydáno v:Oncol Res
Hlavní autoři: Wang, Zhihai, Liao, Kui, Zuo, Wenqi, Liu, Xueliang, Qiu, Zhili, Gong, Zhitao, Liu, Chuan, Zeng, Quan, Qian, Yi, Jiang, Liang, Bu, Youquan, Hong, Suling, Hu, Guohua
Médium: Artigo
Jazyk:Inglês
Vydáno: Cognizant Communication Corporation 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840771/
https://ncbi.nlm.nih.gov/pubmed/28081741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504016X14732772150226
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