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Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53–ROS–Mitochondrial Pathway

NFBD1, a signal amplifier of the p53 pathway, is vital for protecting cells from p53-mediated apoptosis and the early phase of DNA damage response under normal culture conditions. Here we investigated its expression in patients with nasopharyngeal carcinoma (NPC), and we describe the biological func...

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Dettagli Bibliografici
Pubblicato in:Oncol Res
Autori principali: Wang, Zhihai, Liao, Kui, Zuo, Wenqi, Liu, Xueliang, Qiu, Zhili, Gong, Zhitao, Liu, Chuan, Zeng, Quan, Qian, Yi, Jiang, Liang, Bu, Youquan, Hong, Suling, Hu, Guohua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cognizant Communication Corporation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840771/
https://ncbi.nlm.nih.gov/pubmed/28081741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504016X14732772150226
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