Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses

Multi‐omics datasets can provide molecular insights beyond the sum of individual omics. Various tools have been recently developed to integrate such datasets, but there are limited strategies to systematically extract mechanistic hypotheses from them. Here, we present COSMOS (Causal Oriented Search...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Dugourd, Aurelien, Kuppe, Christoph, Sciacovelli, Marco, Gjerga, Enio, Gabor, Attila, Emdal, Kristina B., Vieira, Vitor, Bekker‐Jensen, Dorte B., Kranz, Jennifer, Bindels, Eric.M.J., Costa, Ana S.H., Sousa, Abel, Beltrao, Pedro, Rocha, Miguel, Olsen, Jesper V., Frezza, Christian, Kramann, Rafael, Saez‐Rodriguez, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838823/
https://ncbi.nlm.nih.gov/pubmed/33502086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20209730
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