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Oncometabolites: Unconventional triggers of oncogenic signalling cascades

Cancer is a complex and heterogeneous disease thought to be caused by multiple genetic lesions. The recent finding that enzymes of the tricarboxylic acid (TCA) cycle are mutated in cancer rekindled the hypothesis that altered metabolism might also have a role in cellular transformation. Attempts to...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Sciacovelli, Marco, Frezza, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145802/
https://ncbi.nlm.nih.gov/pubmed/27117029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.04.025
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