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Oncometabolites: Unconventional triggers of oncogenic signalling cascades

Cancer is a complex and heterogeneous disease thought to be caused by multiple genetic lesions. The recent finding that enzymes of the tricarboxylic acid (TCA) cycle are mutated in cancer rekindled the hypothesis that altered metabolism might also have a role in cellular transformation. Attempts to...

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Bibliografische gegevens
Gepubliceerd in:Free Radic Biol Med
Hoofdauteurs: Sciacovelli, Marco, Frezza, Christian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier Science 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5145802/
https://ncbi.nlm.nih.gov/pubmed/27117029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.04.025
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