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Converting networks to predictive logic models from perturbation signalling data with CellNOpt

SUMMARY: The molecular changes induced by perturbations such as drugs and ligands are highly informative of the intracellular wiring. Our capacity to generate large datasets is increasing steadily. A useful way to extract mechanistic insight from the data is by integrating them with a prior knowledg...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Gjerga, Enio, Trairatphisan, Panuwat, Gabor, Attila, Koch, Hermann, Chevalier, Celine, Ceccarelli, Franceco, Dugourd, Aurelien, Mitsos, Alexander, Saez-Rodriguez, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575044/
https://ncbi.nlm.nih.gov/pubmed/32516357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa561
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