Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data

Endothelins (EDN) are peptide hormones that activate a GPCR signalling system and contribute to several diseases, including hypertension and cancer. Current knowledge about EDN signalling is fragmentary, and no systems level understanding is available. We investigated phosphoproteomic changes caused...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Schäfer, Alexander, Gjerga, Enio, Welford, Richard WD, Renz, Imke, Lehembre, Francois, Groenen, Peter MA, Saez‐Rodriguez, Julio, Aebersold, Ruedi, Gstaiger, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683863/
https://ncbi.nlm.nih.gov/pubmed/31464372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20198828
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