Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data

Endothelins (EDN) are peptide hormones that activate a GPCR signalling system and contribute to several diseases, including hypertension and cancer. Current knowledge about EDN signalling is fragmentary, and no systems level understanding is available. We investigated phosphoproteomic changes caused...

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Vydáno v:Mol Syst Biol
Hlavní autoři: Schäfer, Alexander, Gjerga, Enio, Welford, Richard WD, Renz, Imke, Lehembre, Francois, Groenen, Peter MA, Saez‐Rodriguez, Julio, Aebersold, Ruedi, Gstaiger, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683863/
https://ncbi.nlm.nih.gov/pubmed/31464372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20198828
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