Intestinal TMEM16A control luminal chloride secretion in a NHERF1 dependent manner

TMEM16A (Transmembrane protein 16A or Anoctamin1) is a calcium-activated chloride channel. (CaCC),that exerts critical roles in epithelial secretion. However, its localization, function, and regulation in intestinal chloride (Cl(−)) secretion remain obscure. Here, we show that TMEM16A protein abunda...

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Udgivet i:Biochem Biophys Rep
Main Authors: Saha, Tultul, Aoun, Joydeep, Hayashi, Mikio, Ali, Sheikh Irshad, Sarkar, Paramita, Bag, Prasanta Kumar, Leblanc, Normand, Ameen, Nadia, Woodward, Owen M., Hoque, Kazi Mirajul
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838733/
https://ncbi.nlm.nih.gov/pubmed/33537462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2021.100912
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