Anoctamin 6 Contributes to Cl(−) Secretion in Accessory Cholera Enterotoxin (Ace)-stimulated Diarrhea: AN ESSENTIAL ROLE FOR PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE (PIP(2)) SIGNALING IN CHOLERA

Accessory cholera enterotoxin (Ace) of Vibrio cholerae has been shown to contribute to diarrhea. However, the signaling mechanism and specific type of Cl(−) channel activated by Ace are still unknown. We have shown here that the recombinant Ace protein induced I(Cl) of apical plasma membrane, which...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Aoun, Joydeep, Hayashi, Mikio, Sheikh, Irshad Ali, Sarkar, Paramita, Saha, Tultul, Ghosh, Priyanka, Bhowmick, Rajsekhar, Ghosh, Dipanjan, Chatterjee, Tanaya, Chakrabarti, Pinak, Chakrabarti, Manoj K., Hoque, Kazi Mirajul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207189/
https://ncbi.nlm.nih.gov/pubmed/27799301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.719823
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