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Versatile CRISPR/Cas9-mediated mosaic analysis by gRNA-induced crossing-over for unmodified genomes

Mosaic animals have provided the platform for many fundamental discoveries in developmental biology, cell biology, and other fields. Techniques to produce mosaic animals by mitotic recombination have been extensively developed in Drosophila melanogaster but are less common for other laboratory organ...

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發表在:PLoS Biol
Main Authors: Allen, Sarah E., Koreman, Gabriel T., Sarkar, Ankita, Wang, Bei, Wolfner, Mariana F., Han, Chun
格式: Artigo
語言:Inglês
出版: Public Library of Science 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837743/
https://ncbi.nlm.nih.gov/pubmed/33444322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001061
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