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Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation

Surveillance after lung transplantation is critical to the detection of acute cellular rejection (ACR) and prevention of chronic lung allograft dysfunction (CLAD). Therefore, we measured donor-derived cell-free DNA (dd-cfDNA) implementing a clinical-grade, next-generation targeted sequencing assay i...

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Publicat a:ERJ Open Res
Autors principals: Khush, Kiran K., De Vlaminck, Iwijn, Luikart, Helen, Ross, David J., Nicolls, Mark R.
Format: Artigo
Idioma:Inglês
Publicat: European Respiratory Society 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836440/
https://ncbi.nlm.nih.gov/pubmed/33532456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00462-2020
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