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Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation

Surveillance after lung transplantation is critical to the detection of acute cellular rejection (ACR) and prevention of chronic lung allograft dysfunction (CLAD). Therefore, we measured donor-derived cell-free DNA (dd-cfDNA) implementing a clinical-grade, next-generation targeted sequencing assay i...

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Main Authors: Khush, Kiran K., De Vlaminck, Iwijn, Luikart, Helen, Ross, David J., Nicolls, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836440/
https://ncbi.nlm.nih.gov/pubmed/33532456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00462-2020
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