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Adding Insult on Injury: Immunogenic Role for Donor-derived Cell-free DNA?

Donor-derived cell-free DNA (dd-cfDNA) in the blood circulation is an early marker of injury in solid organ transplantation. Here, we review recent evidence that indicates that dd-cfDNA may itself be a trigger of inflammation, thereby adding insult on injury. Early unresolving molecular allograft in...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Dholakia, Shamik, De Vlaminck, Iwijn, Khush, Kiran K.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590963/
https://ncbi.nlm.nih.gov/pubmed/32217943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000003240
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