Exploiting the GTEx resources to decipher the mechanisms at GWAS loci

The resources generated by the GTEx consortium offer unprecedented opportunities to advance our understanding of the biology of human diseases. Here, we present an in-depth examination of the phenotypic consequences of transcriptome regulation and a blueprint for the functional interpretation of gen...

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Publicado en:Genome Biol
Autores principales: Barbeira, Alvaro N., Bonazzola, Rodrigo, Gamazon, Eric R., Liang, Yanyu, Park, YoSon, Kim-Hellmuth, Sarah, Wang, Gao, Jiang, Zhuoxun, Zhou, Dan, Hormozdiari, Farhad, Liu, Boxiang, Rao, Abhiram, Hamel, Andrew R., Pividori, Milton D., Aguet, François, Bastarache, Lisa, Jordan, Daniel M., Verbanck, Marie, Do, Ron, Stephens, Matthew, Ardlie, Kristin, McCarthy, Mark, Montgomery, Stephen B., Segrè, Ayellet V., Brown, Christopher D., Lappalainen, Tuuli, Wen, Xiaoquan, Im, Hae Kyung
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836161/
https://ncbi.nlm.nih.gov/pubmed/33499903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02252-4
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