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A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction

Genetic studies of the transcriptome help bridge the gap between genetic variation and phenotypes. To maximize the potential of such studies, efficient methods to identify expression quantitative trait loci (eQTLs) and perform fine-mapping and genetic prediction of gene expression traits are needed....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liang, Yanyu, Aguet, François, Barbeira, Alvaro N., Ardlie, Kristin, Im, Hae Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930098/
https://ncbi.nlm.nih.gov/pubmed/33658504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21592-8
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