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A Conantokin Peptide Con-T[M8Q] Inhibits Morphine Dependence with High Potency and Low Side Effects

N-methyl-D-aspartate receptor (NMDAR) antagonists have been found to be effective to inhibit morphine dependence. However, the discovery of the selective antagonist for NMDAR GluN2B with low side-effects still remains challenging. In the present study, we report a selective NMDAR GluN2B antagonist c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mar Drugs
Hauptverfasser: Liu, Zhuguo, Yu, Zheng, Yu, Shuo, Zhu, Cui, Dong, Mingxin, Mao, Wenxiang, Hu, Jie, Prorok, Mary, Su, Ruibin, Dai, Qiuyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835912/
https://ncbi.nlm.nih.gov/pubmed/33478061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19010044
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