NR2B-selective Conantokin Peptide Inhibitors of the NMDA Receptor Display Enhanced Antinociceptive Properties Compared to Non-selective Conantokins

NR2B selective inhibitors show lower side-effects in preclinical pain models than non-selective NMDA receptor (NMDAR) antagonists, but it is unclear whether the improved safety of NR2B selective inhibitors is due to their subtype selectivity or to a unique mode of inhibition of the receptor. In the...

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Detalhes bibliográficos
Main Authors: Xiao, Cai, Huang, Yuanyuan, Dong, Mingxin, Hu, Jie, Hou, Shuangshuang, Castellino, Francis J., Prorok, Mary, Dai, Qiuyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621068/
https://ncbi.nlm.nih.gov/pubmed/18992939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.npep.2008.09.003
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