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Specific determinants of conantokins that dictate their selectivity for the NR2B subunit of N-methyl-D-aspartate receptors

Conantokins are naturally-occurring small peptide antagonists of ion flow through NMDA/glycine activated-N-methyl-D-aspartate receptor (NMDAR) ion channels. One member of the conantokin family, conantokin (con)-G, a 17-residue peptide, is selective for NMDARs containing the NR2B subunit, whereas the...

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Hlavní autoři: Sheng, Zhenyu, Prorok, Mary, Castellino, Francis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939254/
https://ncbi.nlm.nih.gov/pubmed/20688135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.07.056
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